Detalles de la búsqueda
1.
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury.
Hepatology;
78(1): 26-44, 2023 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36107019
2.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics.
J Chem Inf Model;
62(1): 196-209, 2022 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34914393
3.
Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.
Handb Exp Pharmacol;
256: 137-165, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31201554
4.
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
Molecules;
24(6)2019 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-30884797
5.
Phallusiasterols A and B: two new sulfated sterols from the Mediterranean tunicate Phallusia fumigata and their effects as modulators of the PXR receptor.
Mar Drugs;
12(4): 2066-78, 2014 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24705503
6.
Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation.
Mar Drugs;
12(6): 3091-115, 2014 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24871460
7.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Biochem Pharmacol;
223: 116134, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38494064
8.
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.
Pharmacol Res;
77: 1-10, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24004655
9.
Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.
Mar Drugs;
12(1): 36-53, 2013 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24368568
10.
Bile acids and bile acid activated receptors in the treatment of Covid-19.
Biochem Pharmacol;
: 115983, 2023 Dec 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38081371
11.
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders.
Biochem Pharmacol;
216: 115776, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37659739
12.
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders.
ACS Omega;
8(6): 5983-5994, 2023 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36816679
13.
Correction to "Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders".
ACS Omega;
8(47): 45163, 2023 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38046314
14.
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Front Oncol;
13: 1140730, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36998446
15.
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Cell Oncol (Dordr);
2023 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37945798
16.
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist.
Org Biomol Chem;
10(31): 6350-62, 2012 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22733410
17.
Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
Mar Drugs;
10(11): 2448-66, 2012 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23203270
18.
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease.
Front Pharmacol;
13: 858137, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35559268
19.
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
Cells;
11(21)2022 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36359879
20.
Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei.
Org Biomol Chem;
9(13): 4856-62, 2011 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21584311